4-Fluorothiophenol → HCID 53829634, compound

HRID 1595580Notes

Reaction equation

HRID 1595580 reaction equation
[CH2:1]([O:3][C:4](=[O:13])[CH:5](Br)[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11])[CH3:2].[F:14][C:15]1[CH:20]=[CH:19][C:18]([SH:21])=[CH:17][CH:16]=1>>[CH2:1]([O:3][C:4](=[O:13])[CH:5]([S:21][C:18]1[CH:19]=[CH:20][C:15]([F:14])=[CH:16][CH:17]=1)[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11])[CH3:2]

Participants

3

Reactant 2

HCID 677894-FluorothiophenolHCID 95580Ethyl 2-bromooctanoate

Product 1

HCID 53829634HCID 53829634, compound

Procedure

2-(4-Fluoro-phenylsulfanyl)-octanoic acid ethyl ester was prepared according to the general method as outlined in example 9. Starting from ethyl-2-bromooctanoate (6.47 g, 24.7 mmol) and 4-fluorothiophenol (3 g, 23.4 mmol). Yield: 6.31 g (90%); clear oil; MS: 299 (M+H)+.

Sources & evidence

ORD record
ord-9291b5c86db349cea8aeeb23738f6002
Source dataset
uspto-grants-2001_09
Patent number
US06288086B1

Reaction notes

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