Ethyl 2-bromooctanoate → HCID 54290310, compound

HRID 1595581Notes

Reaction equation

HRID 1595581 reaction equation
[CH2:1]([O:3][C:4](=[O:13])[CH:5](Br)[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11])[CH3:2].[CH3:14][N:15]1[CH:19]=[CH:18][N:17]=[C:16]1[SH:20]>>[CH2:1]([O:3][C:4](=[O:13])[CH:5]([S:20][C:16]1[N:15]([CH3:14])[CH:19]=[CH:18][N:17]=1)[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11])[CH3:2]

Participants

3

Reactant 2

HCID 95580Ethyl 2-bromooctanoateHCID 178480602HCID 178480602, compound

Product 1

HCID 54290310HCID 54290310, compound

Procedure

2-(1-methyl-1H-imidazol-2-ylsulfanyl)-octanoic acid ethyl ester was prepared according to the general method as outlined in example 9. Starting from ethyl-2-bromooctanoate (12.1 g, 48 mmol) and 1-methyl-2-mercapto imidazole (5 g, 43.8 mmol). Yield: 12 g (96%); clear oil; MS: 285 (M+H)+.

Sources & evidence

ORD record
ord-751ca0c10c854beb8028b3067b49e367
Source dataset
uspto-grants-2001_09
Patent number
US06288086B1

Reaction notes

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