Ethanol, 2-chloro-, 1-(4-methylbenzenesulfonate) → 4-(2-Chloro-ethoxy)-5-methoxy-benzoic acid methyl ester

Participants

Reaction Steps

By using an identical method as in Example 46, 77 g of 4-hydroxy-5-methoxy-benzoic acid methyl ester, 99.2 g of 2-chloroethyl p-toluene sulfonate, 77.7 g of potassium carbonate, and 1.7 g (4.1 mmol) of methyl-tricapryl ammonium chloride was converted to 91.6 g of the title compound: mass spectrum (electrospray, m/e,): M+H 245.0

Provenance & Evidence