Pyridinium chloride → HCID 178487886, compound

Participants

Reaction Steps

Using an analogous procedure to that described in Example 141, 218.6 mg (1 mmol) of 4-chloro-6-methoxy-3-quinolinecarbonitrile in 10 mL of 2-ethoxyethanol and in the presence of 115.6 mg (1 mmol) of pyridine hydrochloride was reacted with 161.0 mg (1.2 mmol) of 5-aminobenzotriazole to give 302.9 mg (95.8%) of the product as a yellow solid, m.p.>250° C., mass (electrospray, m/e): M+H 316.9. HRCIMS calcd: 316.107 for C17H12N6O(M+), obsd 316.1081

Provenance & Evidence