HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → 6-(1,4-Dioxa-8-azaspiro[4,5]dec-8-yl)-1,3,5-triazine-2,4-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 1,3,5-Triazine-2,4-diamine, 6-chloro- | HCID 18831 | — |
| Reactant | 1,4-Dioxa-8-azaspiro(4.5)decane | HCID 67435 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 6-(1,4-Dioxa-8-azaspiro[4,5]dec-8-yl)-1,3,5-triazine-2,4-diamine | HCID 9816436 | — |
Reaction Steps
A mixture of 2,4-diamino-6-chloro-1,3,5-triazine (2 g, 14 mmol), 1,4-dioxa-8-azaspiro[4.5]decane (3 g, 21 mmol), and KOH (100 mg, 1.8 mmol) in dioxane (10 mL) and ethanol (40 mL) was heated at reflux overnight, diluted with water, and filtered. The precipitate was rinsed with water and dried under vacuum to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06288228B1 |
| Source dataset | uspto-grants-2001_09 |
| ORD ID | ord-f1655bbaf844497da65eb9f6a2f0e4d7 |
| Source note | uspto-grants-2001_09 |