HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylacetylene → 4-(Phenylethynyl)benzil
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylacetylene | HCID 10821 | — |
| Reactant | 1-(4-Bromophenyl)-2-phenylethane-1,2-dione | HCID 236701 | — |
| Catalyst | HCID 178418476 | HCID 178418476 | — |
| Solvent | Diethylamine | HCID 8021 | — |
| Product | 4-(Phenylethynyl)benzil | HCID 11088191 | — |
Reaction Steps
4-Bromobenzil (10.0 g, 0.0346 mol), phenylacetylene (3.88 g, 0.0380 mol), and (PPh3)2PdCl2 (0.121 g, 0.0002 mol) in diethylamine (950 mL) is stirred at ambient temperature for 72 hours, followed by concentration to dryness. The residue is then taken up in methylene chloride. Standard aqueous workup followed by recrystallization from 2-propanol gives the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06288188B1 |
| Source dataset | uspto-grants-2001_09 |
| ORD ID | ord-071f6f28603845aead5c2722c666b91c |
| Source note | uspto-grants-2001_09 |