HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 5-Undecen-4-one, 7-ethyl-2-methyl-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 2-Ethylhexanal | HCID 31241 | — |
| Reactant | 4-Undecanol, 7-ethyl-2-methyl- | HCID 97948 | — |
| Solvent | Methyl Isobutyl Ketone | HCID 7909 | — |
| Product | 5-Undecen-4-one, 7-ethyl-2-methyl- | HCID 73557051 | — |
Reaction Steps
In particular, the process of the invention is suitable for preparing 7-ethyl-2-methyl-4-undecanol (tetradecanol) by aldol condensation of methyl isobutyl ketone and 2-ethylhexanal at 90-110° C. in the presence of a 40-50% strength aqueous sodium hydroxide solution to form 7-ethyl-2-methylundec-5-en-4-one with subsequent hydrogenation to give the above-mentioned alcohol. The hydrogenation catalyst used here is, preferably, a nickel catalyst supported on kieselguhr.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06288288B1 |
| Source dataset | uspto-grants-2001_09 |
| ORD ID | ord-c70cf4e6d8ca4f3a9aa7f3b26b38ddd8 |
| Source note | uspto-grants-2001_09 |