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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1596038Generated: October 30, 2026

Sodium Hydroxide → 5-Undecen-4-one, 7-ethyl-2-methyl-

https://huagongshe.com/reaction/1596038

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactant2-EthylhexanalHCID 31241—
Reactant4-Undecanol, 7-ethyl-2-methyl-HCID 97948—
SolventMethyl Isobutyl KetoneHCID 7909—
Product5-Undecen-4-one, 7-ethyl-2-methyl-HCID 73557051—

Reaction Steps

In particular, the process of the invention is suitable for preparing 7-ethyl-2-methyl-4-undecanol (tetradecanol) by aldol condensation of methyl isobutyl ketone and 2-ethylhexanal at 90-110° C. in the presence of a 40-50% strength aqueous sodium hydroxide solution to form 7-ethyl-2-methylundec-5-en-4-one with subsequent hydrogenation to give the above-mentioned alcohol. The hydrogenation catalyst used here is, preferably, a nickel catalyst supported on kieselguhr.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06288288B1
Source datasetuspto-grants-2001_09
ORD IDord-c70cf4e6d8ca4f3a9aa7f3b26b38ddd8
Source noteuspto-grants-2001_09