Ethylene Glycol → HCID 21701038, compound

Participants

Reaction Conditions

Reaction Steps

Tetrahydrofuran solvent (500 g), thiophene (1.0 mole), represented by Chemical Formula 2a below, ethylene glycol (0.22 mole) and 2-hydroxyethyl acrylate (1.2 mole), represented by Chemical Formula 3a, are introduced into a 2-liter flask, and the mixture is stirred at 70° C. for 24 hours. After the reaction is completed, the solvent and excess 2-hydroxyethyl acrylate are removed by using a rotary evaporator, and the residue is distilled in vacuo to obtain pure 2-hydroxyethyl 7-thiabicyclo[2.2.1]hept-5-ene-2-carboxylate represented by Chemical Formula 101 below (yield: 80%).

Provenance & Evidence