HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1596129Generated: November 4, 2026
Acrylic Acid → 7-Thiabicyclo[2.2.1]hept-5-ene-2-carboxylic acid
https://huagongshe.com/reaction/1596129
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acrylic Acid | HCID 6581 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | Thiophene | HCID 8030 | — |
| Product | 7-Thiabicyclo[2.2.1]hept-5-ene-2-carboxylic acid | HCID 22619028 | — |
Reaction Steps
Tetrahydrofuran solvent (500 g), acrylic acid (1.2 mole) and thiophene (1.0 mole) are introduced into a 2-liter flask. After stirring at 700° C. for 24 hours, the solvent and excessive acrylic acid are removed by using a rotary evaporator. The residue is distilled in vacuo to obtain pure 7-thiabicyclo[2.2.1]hept-5-ene-2-carboxylic acid of Chemical Formula 142 (yield: 80%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06291131B1 |
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| Source dataset | uspto-grants-2001_09 |
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| ORD ID | ord-7cf5ee0f68e8485391384bd50723dcd8 |
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| Source note | uspto-grants-2001_09 |
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