HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 4-(2-Oxiranylmethoxy)phthalonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | (Oxiran-2-yl)methyl 3-nitrobenzene-1-sulfonate | HCID 286836 | — |
| Reactant | 4-Hydroxybenzene-1,2-dicarbonitrile | HCID 3875765 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 4-(2-Oxiranylmethoxy)phthalonitrile | HCID 21701950 | — |
Reaction Steps
A stirred suspension of 4-hydroxyphthalonitrile (3.5 g; 24.3 mmol), K2CO3 (4.03 g; 29.2 mmol) and 2-{[(3-nitrophenyl)sulfonyloxy]methyl}-oxirane (6.50 g; 25.0 mmol; see Example B above) in MeCN (170 mL) was refluxed for 1.5 h. The cooled reaction mixture was filtered, the filtrate concentrated and the solid residue recrystallized from IPA to give the sub-title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06291475B1 |
| Source dataset | uspto-grants-2001_09 |
| ORD ID | ord-bd65396e053b4c58bbe1c2cd5fe5b378 |
| Source note | uspto-grants-2001_09 |