Ethyl cyanoacetate → Ethyl 2-cyano-2-cyclopentylideneacetate

HRID 1596466Notes

Reaction equation

[C:1]1(=O)[CH2:5][CH2:4][CH2:3][CH2:2]1.[C:7]([CH2:9][C:10]([O:12][CH2:13][CH3:14])=[O:11])#[N:8]>>[CH2:2]1[CH2:3][CH2:4][CH2:5][C:1]1=[C:9]([C:7]#[N:8])[C:10]([O:12][CH2:13][CH3:14])=[O:11]

Participants

Reactant 2

HCID 7764Ethyl cyanoacetate

HCID 8452Cyclopentanone

Product 1

HCID 223257Ethyl 2-cyano-2-cyclopentylideneacetateYield 69%

Procedure

The sub-title compound was prepared in a 69% yield analogously to the method described in Organic Synthesis, 39, 25 (1959) from cyclopentanone and ethyl cyanoacetate.

Sources & evidence

ORD record: ord-823d59eae23d41a1a8053ee2af64bf52
Source dataset: uspto-grants-2001_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06291475B1

Reaction notes

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