Hydrogen Peroxide → HCID 9840080, compound

Participants

Reaction Steps

Example 3 was prepared by the following procedure. To a stirred solution of 20 mg of 2-(4benzyl-cyclohexylidenemethyl)-1H-benzimidazole in 10 mL of THF cooled in an ice bath was added 1 mL of 1M borane•THF. After stirring for 24 h warming to room temperature, 0.5 mL of water was added followed by 0.5 mL of 6N sodium hydroxide and 0.5 mL of 30% hydrogen peroxide. After 30 min, the solution was diluted with 100 mL of chloroform, washed 2×10 mL of water, dried over magnesium sulfate and concentrated to dryness.

Provenance & Evidence