反应详情

382 mg of 3-nitrobenzenesulphonyl chloride were added at 0° C. to a solution of 500 mg of (1d) in 4 ml of pyridine. After a reaction time of 1 h at 0° C. and 2 h at room temperature, the mixture was concentrated, treated with 1 N HCl and extracted with dichloromethane. After drying over MgSO4, the solvent was removed and 649 mg of a solid were obtained.

1. concentrationAfter a reaction time of 1 h at 0° C. and 2 h at room temperature, the mixture was concentrated
2. additiontreated with 1 N HCl
3. extractionextracted with dichloromethane
4. dry with materialAfter drying over MgSO4
5. customthe solvent was removed