Benzoyl chloride → Ethyl 3-benzoylamino-3-(3-nitrophenyl)-propionate

HRID 1596565Notes

Reaction equation

HRID 1596565 reaction equation
Cl.[NH2:2][CH:3]([C:10]1[CH:15]=[CH:14][CH:13]=[C:12]([N+:16]([O-:18])=[O:17])[CH:11]=1)[CH2:4][C:5]([O:7][CH2:8][CH3:9])=[O:6].[C:19](Cl)(=[O:26])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[C:19]([NH:2][CH:3]([C:10]1[CH:15]=[CH:14][CH:13]=[C:12]([N+:16]([O-:18])=[O:17])[CH:11]=1)[CH2:4][C:5]([O:7][CH2:8][CH3:9])=[O:6])(=[O:26])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 7412Benzoyl chlorideHCID 16188861Ethyl 3-amino-3-(3-nitrophenyl)propanoate hydrochloride

Product 1

HCID 3816281Ethyl 3-benzoylamino-3-(3-nitrophenyl)-propionate

Procedure

Corresponding to Example 3a, 5.0 g of (1b) were acetylated by addition of benzoyl chloride. A white solid was obtained (yield: 3.3 g).

Workup

  1. customA white solid was obtained (yield: 3.3 g)

Sources & evidence

ORD record
ord-972ec96282204ba8a8ae975c427234f7
Source dataset
uspto-grants-2001_09
Patent number
US06291503B1

Reaction notes

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