3-Nitrobenzenesulfonyl chloride → Ethyl 3-benzoylamino-3-(3-(-3-nitrobenzenesulphonylamino)-phenyl)-propionate

HRID 1596567Notes

Reaction equation

HRID 1596567 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([CH:8]([NH:15][C:16](=[O:23])[C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[CH2:9][C:10]([O:12][CH2:13][CH3:14])=[O:11])[CH:5]=[CH:6][CH:7]=1.[N+:24]([C:27]1[CH:28]=[C:29]([S:33](Cl)(=[O:35])=[O:34])[CH:30]=[CH:31][CH:32]=1)([O-:26])=[O:25]>>[C:16]([NH:15][CH:8]([C:4]1[CH:5]=[CH:6][CH:7]=[C:2]([NH:1][S:33]([C:29]2[CH:30]=[CH:31][CH:32]=[C:27]([N+:24]([O-:26])=[O:25])[CH:28]=2)(=[O:34])=[O:35])[CH:3]=1)[CH2:9][C:10]([O:12][CH2:13][CH3:14])=[O:11])(=[O:23])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

Participants

3

Procedure

Corresponding to Example 3c, 2.60 g of (4b) were reacted with 3-nitrophenylsulphonyl chloride. A solid was obtained (yield: 1.76 g).

Workup

  1. customA solid was obtained (yield: 1.76 g)

Sources & evidence

ORD record
ord-f9139542c89948fe993ba4bce202da5a
Source dataset
uspto-grants-2001_09
Patent number
US06291503B1

Reaction notes

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