Lithium Hydroxide → HCID 86585191, compound

Participants

Reaction Steps

A solution of ester 6 (614 mg, 0.97 mmol) and lithium hydroxide (62 mg, 1.5 mmol) in THF/H2O (1:1, 20 mL) was stirred at 23° C. for 72 h. The mixture was acidified with 1N HC1 and extracted with EtOAc. The organic portion was washed with brine, dried (Na2SO4), filtered and concentrated in vacuo to give 430 mg of the above titled compound.

Provenance & Evidence