4-Vinylpyridine → HCID 22975755, compound

HRID 1596685Notes

Reaction equation

HRID 1596685 reaction equation
[CH2:1]1[C:6]2([CH2:11][CH2:10][CH:9]([CH2:12][C:13]([O:15][CH2:16][CH3:17])=[O:14])[CH2:8][CH2:7]2)[CH2:5][CH2:4][NH:3][CH2:2]1.[CH:18]([C:20]1[CH:25]=[CH:24][N:23]=[CH:22][CH:21]=1)=[CH2:19]>C(#N)C>[N:23]1[CH:24]=[CH:25][C:20]([CH2:18][CH2:19][N:3]2[CH2:2][CH2:1][C:6]3([CH2:11][CH2:10][CH:9]([CH2:12][C:13]([O:15][CH2:16][CH3:17])=[O:14])[CH2:8][CH2:7]3)[CH2:5][CH2:4]2)=[CH:21][CH:22]=1

Participants

4

Reactant 2

HCID 75024-VinylpyridineHCID 22975760HCID 22975760, compound

Product 1

HCID 22975755HCID 22975755, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

A solution of 0.48 g (2.0 mmol) of the intermediate from Example 1, Step C and 0.21 g (2.0 mmol) 4-vinylpyridine in 6 ml acetonitrile were heated at 80° C. over night. The solvent was removed under reduced pressure, and the remaining solid title compound was purified by stirring several times with tert.-butylmethylether, filtered with suction, and dried in vacuo.

Workup

  1. customThe solvent was removed under reduced pressure
  2. customthe remaining solid title compound was purified
  3. filtrationfiltered with suction
  4. customdried in vacuo

Sources & evidence

ORD record
ord-709b6fb7b4004523a000aae6d8dd37f2
Source dataset
uspto-grants-2001_09
Patent number
US06291469B1

Reaction notes

Loading…