HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 131632219, compound → HCID 131722859, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 131632219 | HCID 131632219 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 131722859 | HCID 131722859 | 80% |
Reaction Steps
The Boc-Gly-Phe-Leu-OBzl (1.7 g) obtained in Example 19 was dissolved in a mixed solution of ethyl acetate (30 ml) and methanol (30 ml), and added with 5% Pd-C (1.5 g) to perform catalytic reduction. The reaction mixture was filtered and the filtrate was evaporated to dryness under reduced pressure to give the title compound (1.15 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06291671B1 |
| Source dataset | uspto-grants-2001_09 |
| ORD ID | ord-253f9d4753ac4352b9a6ab08f8028dad |
| Source note | uspto-grants-2001_09 |