4-Aminocyclohexanol → 1-cyclopentyl-3-(2-fluoro-3,5-dimethoxy-phenyl)-7-(trans-4-hydroxy-cyclohexylamino)-3,4-dihydro-1H-pyrimido[4,5-d]pyrimidin-2-one
Reaction equation
[CH:1]1([N:6]2[C:7](=[O:30])[N:8]([c:19]3[c:20]([F:29])[c:21]([O:27][CH3:28])[cH:22][c:23]([O:25][CH3:26])[cH:24]3)[CH2:9][c:10]3[c:11]2[n:12][c:13]([S:16]([CH3:17])=[O:18])[n:14][cH:15]3)[CH2:2][CH2:3][CH2:4][CH2:5]1.[OH:31][CH:32]1[CH2:33][CH2:34][CH:35]([NH2:38])[CH2:36][CH2:37]1>>[CH:1]1([N:6]2[C:7](=[O:30])[N:8]([c:19]3[c:20]([F:29])[c:21]([O:27][CH3:28])[cH:22][c:23]([O:25][CH3:26])[cH:24]3)[CH2:9][c:10]3[c:11]2[n:12][c:13]([NH:38][CH:35]2[CH2:34][CH2:33][CH:32]([OH:31])[CH2:37][CH2:36]2)[n:14][cH:15]3)[CH2:2][CH2:3][CH2:4][CH2:5]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-ffa831a187f44c639eb7272947ed07ca
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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