5,6-dichloropyridine-3-carbonyl Chloride → 2,3-Dichloro-5-[4-(2,6-dichloro-4-nitrobenzyl)benzoyl]pyridine

HRID 1597195Notes

Reaction equation

HRID 1597195 reaction equation
[Cl:1][C:2]1[C:3]([Cl:11])=[N:4][CH:5]=[C:6]([CH:10]=1)[C:7](Cl)=[O:8].[CH2:12]([C:19]1[C:24]([Cl:25])=[CH:23][C:22]([N+:26]([O-:28])=[O:27])=[CH:21][C:20]=1[Cl:29])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[Cl:11][C:3]1[C:2]([Cl:1])=[CH:10][C:6]([C:7](=[O:8])[C:16]2[CH:17]=[CH:18][C:13]([CH2:12][C:19]3[C:20]([Cl:29])=[CH:21][C:22]([N+:26]([O-:28])=[O:27])=[CH:23][C:24]=3[Cl:25])=[CH:14][CH:15]=2)=[CH:5][N:4]=1

Participants

3

Reactant 2

HCID 27821565,6-dichloropyridine-3-carbonyl ChlorideHCID 216993324-Benzyl-3,5-dichloronitrobenzene

Product 1

HCID 216994412,3-Dichloro-5-[4-(2,6-dichloro-4-nitrobenzyl)benzoyl]pyridineYield 28.5%

Procedure

The title compound was prepared as pale yellow crystals at yield of 28.5%, in a similar manner as in Reference Example 1, by the reaction of 5,6-dichloronicotinoylchloride and 4-benzyl-3,5-dichloronitrobenzene.

Sources & evidence

ORD record
ord-3b2ce596a0c3415cb6faf1118a550d0b
Source dataset
uspto-grants-2001_09
Patent number
US06294536B1

Reaction notes

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