Morpholine → HCID 15907531, compound

HRID 1597291Notes

Reaction equation

HRID 1597291 reaction equation
[CH2:1]([N:3]1[C:11]2[N:10]=[C:9]([CH2:12][CH3:13])[NH:8][C:7]=2[C:6](=S)[NH:5][C:4]1=[S:15])[CH3:2].[NH:16]1[CH2:21][CH2:20][O:19][CH2:18][CH2:17]1>CC(C)=O>[CH2:1]([N:3]1[C:11]2[N:10]=[C:9]([CH2:12][CH3:13])[NH:8][C:7]=2[C:6]([N:16]2[CH2:21][CH2:20][O:19][CH2:18][CH2:17]2)=[N:5][C:4]1=[S:15])[CH3:2]

Participants

4

Reactant 2

HCID 8083MorpholineHCID 15907530HCID 15907530, compound

Product 1

HCID 15907531HCID 15907531, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

The product of stage (i) (14.42 g) was refluxed in 78.4 ml (900 mmoles) of morpholine for 30 hours. After cooling to room temperature the reaction product was suspended in 100 ml of acetone and the title product (16.49 g) collected and washed.

Workup

  1. customthe title product (16.49 g) collected
  2. washwashed

Sources & evidence

ORD record
ord-c29afa5c24f64c46b7be330c315f9a8b
Source dataset
uspto-grants-2001_09
Patent number
US06294541B1

Reaction notes

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