HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-methylaminobenzoate → Methyl4-{N-[1(S)(3-methoxymethoxyphenyl)-2-(3-(S)-methoxymethoxypyrrolidin-1-yl)-ethyl]-N-methylamino}benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-methylaminobenzoate | HCID 140375 | — |
| Reactant | 1-(S)-(3-methoxymethoxyphenyl)-2-(3-(S)-methoxymethoxypyrrolidin-1-yl)ethanol | HCID 20640583 | — |
| Reactant | 2-(R)-(3-methoxymethoxyphenyl)-2-(3-(S)-methoxymethoxypyrrolidin-1-yl)ethanol | HCID 20640587 | — |
| Product | Methyl4-{N-[1(S)(3-methoxymethoxyphenyl)-2-(3-(S)-methoxymethoxypyrrolidin-1-yl)-ethyl]-N-methylamino}benzoate | HCID 20640608 | 60% |
Reaction Steps
This was prepared from the mixture of 2-(R)-(3-methoxymethoxyphenyl)-2-(3-(S)-methoxymethoxypyrrolidin-1-yl)ethanol and 1-(S)-(3-methoxymethoxyphenyl)-2-(3-(S)-methoxymethoxypyrrolidin-1-yl)ethanol and methyl 4-methylaminobenzoate in 60% yield according to a procedure similar to that described in Example 1 (i).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06294557B1 |
| Source dataset | uspto-grants-2001_09 |
| ORD ID | ord-a2832f8095b74698b02019423ea133a2 |
| Source note | uspto-grants-2001_09 |