Disiloxane → HCID 54482327, compound

HRID 1597433Notes

Reaction equation

HRID 1597433 reaction equation
C[SiH](C)[O:3][CH:4]1[C:8](C)(C)[CH2:7][O:6][C:5]1=[O:11].[CH3:13][S:14]([C:17]1[CH:22]=[CH:21][C:20]([O:23][C:24]2[CH:29]=[CH:28][C:27]([O:30][C:31]([F:34])([F:33])[F:32])=[CH:26][CH:25]=2)=[CH:19][CH:18]=1)(=[O:16])=[O:15].[SiH3]O[SiH3]>>[OH:3][C@H:4]([CH2:8][CH2:7][OH:6])[C:5](=[O:11])[CH2:13][S:14]([C:17]1[CH:18]=[CH:19][C:20]([O:23][C:24]2[CH:29]=[CH:28][C:27]([O:30][C:31]([F:32])([F:33])[F:34])=[CH:26][CH:25]=2)=[CH:21][CH:22]=1)(=[O:16])=[O:15]

Participants

4

Reactant 3

HCID 123318DisiloxaneHCID 102866141-(Methanesulfonyl)-4-[4-(trifluoromethoxy)phenoxy]benzeneHCID 131722871HCID 131722871, compound

Product 1

HCID 54482327HCID 54482327, compound

Procedure

Reaction of (R)-dihydro-3-tertbuty]dimethylsilyloxy-4,4-dimethyl-2(3H)-furanone with 4-(4′-trifluoromethoxyphenyloxy)-phenyl methyl sulfone as in Example 126A followed by silyl ether deprotection as in Example 125B gave the title compound.

Sources & evidence

ORD record
ord-35889ac065c5400a8dcda2a33232dd53
Source dataset
uspto-grants-2001_09
Patent number
US06294573B1

Reaction notes

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