HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylpiperazine → HCID 54403410, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | 1,1'-Thiocarbonyldiimidazole | HCID 80264 | — |
| Reactant | Ethylacetate methanol | HCID 21584119 | — |
| Product | HCID 54403410 | HCID 54403410 | — |
Reaction Steps
The title compound (490 mg) was prepared from 18.7 g (104.8 mmol) of thiocarbonyldiimidazole and 10 g (99.8 mmol) of 1-methyl piperazine according to the method of intermediate 53, followed by the procedure outlined for the preparation of Intermediate 60 and purification via silica gel chromatography using MeOH/EtOAc (3:17) as eluent: TLC (MeOH/EtOAc (1:9)): Rf=0.15.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06294580B1 |
| Source dataset | uspto-grants-2001_09 |
| ORD ID | ord-583449c137284e5b94b29ab24ad43a4f |
| Source note | uspto-grants-2001_09 |