Benzeneacetic acid, 4-bromo- → 4-[4-(4-Bromophenyl)-5-oxo-2,5-dihydro-3-furanyl]-2-(fluoro)benzenesulfonamide

HRID 1597571Notes

Reaction equation

HRID 1597571 reaction equation
Br[CH2:2][C:3]([C:5]1[CH:10]=[CH:9][C:8]([S:11]([NH2:14])(=[O:13])=[O:12])=[C:7]([F:15])[CH:6]=1)=O.[Br:16][C:17]1[CH:22]=[CH:21][C:20]([CH2:23][C:24]([OH:26])=[O:25])=[CH:19][CH:18]=1>>[Br:16][C:17]1[CH:18]=[CH:19][C:20]([C:23]2[C:24](=[O:26])[O:25][CH2:2][C:3]=2[C:5]2[CH:10]=[CH:9][C:8]([S:11]([NH2:14])(=[O:13])=[O:12])=[C:7]([F:15])[CH:6]=2)=[CH:21][CH:22]=1

Participants

3

Reactant 2

HCID 74654Benzeneacetic acid, 4-bromo-HCID 223166704-Bromoacetyl-2-(fluoro)benzenesulfonamide

Product 1

HCID 223169044-[4-(4-Bromophenyl)-5-oxo-2,5-dihydro-3-furanyl]-2-(fluoro)benzenesulfonamide

Procedure

The title compound was prepared according to the procedure of Example 32 using 4-bromoacetyl-2-(fluoro)benzenesulfonamide from step 2 instead of [2-bromo-1-[4-methylsulfonyl)phenyl]ethanone, 4-bromophenylacetic acid instead of 4-(3-thienyl)phenylacetic acid.

Sources & evidence

ORD record
ord-8aab2e9a3a144ee8a128181109023992
Source dataset
uspto-grants-2001_09
Patent number
US06294558B1

Reaction notes

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