HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloropyridine hydrochloride → Ethyl 1-(pyridin-4-yl)piperidine-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloropyridine hydrochloride | HCID 81852 | — |
| Reactant | Ethyl nipecotate | HCID 98969 | — |
| Product | Ethyl 1-(pyridin-4-yl)piperidine-3-carboxylate | HCID 12895985 | — |
Reaction Steps
Ethyl (+) nipecotate (7.0 g, 44.53 mmol) was reacted with 4-chlorpyridine hydrochloride (6.67 g, 44.53 mmol) as described for 21-1 to give the title compound as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06294549B1 |
| Source dataset | uspto-grants-2001_09 |
| ORD ID | ord-de120209cfd646989a8d65c41670051f |
| Source note | uspto-grants-2001_09 |