HuagongsheHuagongshe Chemistry Print Report · For research reference only
Selenium Dioxide → 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Selenium Dioxide | HCID 24007 | — |
| Reactant | 4,5-Dimethyl-1,3-dioxol-2-one | HCID 142210 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one | HCID 10510878 | — |
Reaction Steps
A mixture of 4,5-dimethyl-2-oxo-1,3-dioxolene (1 mmol) and selenium dioxide (2.5 mmol) in dioxane was heated at reflux for 1 h. Evaporation, extraction and chromatography gave 5-methyl-4-hydroxymethyl-2-oxo-1,3-dioxolene as a yellow oil. TLC: Rf=0.5, 5% MeOH-dichloromethane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06294672B1 |
| Source dataset | uspto-grants-2001_09 |
| ORD ID | ord-b41a1ea1f39e42d5b9c81923e6336215 |
| Source note | uspto-grants-2001_09 |