Sodium Hydroxide → (1-Cyanocyclohexyl)acetic acid

HRID 1597677Notes

Reaction equation

C([O:3][C:4](=[O:14])[CH2:5][C:6]1([C:12]#[N:13])[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1)C.[OH-].[Na+]>>[C:12]([C:6]1([CH2:5][C:4]([OH:14])=[O:3])[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1)#[N:13]

Participants

Reactant 2

HCID 14798Sodium Hydroxide

HCID 10965422ETHYL (1-CYANOCYCLOHEXYL)ACETATE

Product 1

HCID 11073797(1-Cyanocyclohexyl)acetic acid

Procedure

(1-Cyanocyclohexyl)acetic acid ethyl ester is reacted with aqueous sodium hydroxide solution using the methodology disclosed at Column 15, Method C, Step B of U.S. Pat. No. 5,132,451 which is herein incorporated by reference to afford the title product.

Sources & evidence

ORD record: ord-b3b4fbd5ce844587b0259431da5825e4
Source dataset: uspto-grants-2001_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06294690B1

Reaction notes

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