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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1597720Generated: October 25, 2026

Topotecan → Camptothecin

https://huagongshe.com/reaction/1597720

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTopotecanHCID 60700—
Reactant9-AminocamptothecinHCID 72402—
Reactant10,11-Methylenedioxy-20-camptothecinHCID 72403—
ReactantHydroxycamptothecinHCID 97226—
Reactant9-Chloro-10,11-methylene-dioxycamptothecinHCID 468671—
ReactantRubitecanHCID 472335—
ProductCamptothecinHCID 24360—

Reaction Steps

10-hydroxycamptothecin; topotecan; 9-aminocamptothecin; 9-nitrocamptothecin; 10,11-methylenedioxycamptothecin; 9-amino-10,11 methlenedioxycamptothecin; 9-chloro-10,11-methylene-dioxycamptothecin; and mixtures thereof.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05736156
Source datasetuspto-grants-1998_04
ORD IDord-2137cff5d6f6483e93c4c818e525850d
Source noteuspto-grants-1998_04