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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1597939Generated: October 30, 2026

6-Nitroindoline → HCID 18932872, compound

https://huagongshe.com/reaction/1597939

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-NitroindolineHCID 29757—
Reactant4-Chloro-6,7-dimethoxyquinazolineHCID 2769364—
SolventIsopropanolHCID 3776—
ProductHCID 18932872HCID 1893287291%

Reaction Steps

Utilizing a procedure analogous to that described in Example 1, this product was prepared in 91% yield from 6-nitro-indoline (1 eq.) and 4-chloro-6,7-dimethoxy-quinazoline (1.0 eq) in i-PrOH. (M.P. 275° C. (dec); GC-MS: 352 (M+); anal. RP18-HPLC RT: 4.30 min.).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05736534
Source datasetuspto-grants-1998_04
ORD IDord-f437f57e4bec4e90a142f9ab03d71c40
Source noteuspto-grants-1998_04