HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Methyl-2,3-dihydro-1H-indole → 7-Methoxy-4-(7-methyl-2,3-dihydro-indol-1-yl)-quinazoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Methyl-2,3-dihydro-1H-indole | HCID 12377788 | — |
| Reactant | 4-Chloro-7-methoxy-quinazoline | HCID 18925078 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 7-Methoxy-4-(7-methyl-2,3-dihydro-indol-1-yl)-quinazoline | HCID 18932840 | 79% |
Reaction Steps
Utilizing a procedure analogous to that described in Example 1 this product was prepared in 79% yield from 7-methyl-indoline (1.1 eq.), and 4-chloro-7-methoxy-quinazoline (1.0 eq) in i-PrOH. (M.P. 157°-160° C. (dec); LC-MS: 292 (MH+); anal. RP18-HPLC RT: 4.30 min.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05736534 |
| Source dataset | uspto-grants-1998_04 |
| ORD ID | ord-2ac30c1ddcb24ee992f04b7e91b4d7bf |
| Source note | uspto-grants-1998_04 |