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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1597973Generated: October 26, 2026

6-Chloro-2,3-dihydro-1h-indole → 4-(6-Chloro-2,3-dihydro-indol-1-yl)-6-methoxy-quinazoline

https://huagongshe.com/reaction/1597973

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Chloro-2,3-dihydro-1h-indoleHCID 258567—
Reactant4-Chloro-6-methoxyquinazolineHCID 11183174—
Product4-(6-Chloro-2,3-dihydro-indol-1-yl)-6-methoxy-quinazolineHCID 1893281877%

Reaction Steps

Utilizing a procedure analogous to that described in Example 1, this product was prepared in 77% yield from 6-chloro-indoline and 4-chloro-6-methoxy-quinazoline. (M.P. 243° C.; LC-MS: 312 (MH+)).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05736534
Source datasetuspto-grants-1998_04
ORD IDord-48efce1b239f47cd86747a98edd1ee15
Source noteuspto-grants-1998_04