HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → HCID 15462362, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | HCID 18349331 | HCID 18349331 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 15462362 | HCID 15462362 | — |
Reaction Steps
3,5-diiodo-4-(4'-methoxyphenoxy)-N-methyl benzamide (Compound 8) was prepared by way of 3,5-diiodo-4-(4'-methoxyphenoxy)benzoyl chloride (see, Example 1.5). The acid chloride was reacted with excess methylamine in tetrahydrofuran at ambient temperature (1 hour), filtered to remove methylamine-hydrochloride precipitate, the solvent evaporated and the product crystallized from 95% ethanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05736576 |
| Source dataset | uspto-grants-1998_04 |
| ORD ID | ord-0aa2f0aecf5948668a76eb3347d5486b |
| Source note | uspto-grants-1998_04 |