Sodium Hydroxide → HCID 11010263, compound

Participants

Reaction Steps

To a solution of the acetate from step 2 herein (36 mg, 0.13 mmol) in dry MeOH (1.3 ml), at room temperature, was added 1N NaOH (0.14 ml, 1.1 eq.) and the solution was stirred for 45 minutes. It was then poured in H2O and the aqueous phase was extracted 3× with CH2Cl2. The combined organic extracts were dried over MgSO4, the solids were filtered and the solvent evaporated to give 30 mg (96%) of the pure titled alcohol.

Provenance & Evidence