Triphenylphosphine → HCID 56631310, compound

Participants

Reaction Steps

To a solution of the alcohol from step 3 herein (62 mg, 0.25 mmol) in dry THF (2.5 ml), at room temperature, under argon, were added successively Ph3P (66 mg, 1 eq.), DEAD (40 μl, 1 eq.) and (PhO)2 PON3 (54 μl, 1 eq.) and the solution was stirred for 18 hours. The THF was evaporated and the crude oil was purified by flash chromatography (silica gel, 95:5 hexanes/EtOAc) to give 38 mg (56%) of the titled azide as a clear oil.

Provenance & Evidence