m-Chloroperbenzoic acid → 3-(2,6-Dichloro-4-trifluoromethylphenyl)-1-methyl-5-methylsulfinylpyrazole

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Reaction Steps

A 0.3 g quantity of 70% m-chloroperbenzoic acid was slowly added to 0.3 g of 3-(2,6-dichloro-4-trifluoromethylphenyl)-1-methyl-5-methylsulfenylpyrazole (compound 1) in 20 ml of anhydrous chloroform at room temperature with stirring, followed by stirring for 3 hours. The reaction mixture was poured into a saturated aqueous solution of sodium hydrogencarbonate, an organic layer was then separated off, washed with 5% aqueous sodium hydroxide solution and with brine and dried over anhydrous magnesium sulfate. The solvent was thereafter distilled off under reduced pressure, giving 0.3 g of the desired compound in the form of white crystals (quantitative crude yield).

Provenance & Evidence