HCID 18929395, compound → HCID 18929420, compound

Participants

Reaction Steps

A suspension of 0.15 g of 3-(2,6-dichloro-4-trifluoromethylphenyl)-1-methyl-5-methylsulfenyl-4-nitropyrazole (compound 13) and 0.1 g of 10% palladium carbon in ethanol was stirred for 1 hour while introducing hydrogen gas into the mixture at room temperature at atmospheric pressure. The reaction mixture was filtered through Celite, the filtrate was concentrated under reduced pressure, and the resulting residue was purified by column chromatography on silica gel (eluent: ether/hexane=1/4) to obtain 0.6 g of the desired compound in the form of a consistent liquid (yield 67.3%).

Provenance & Evidence