Methylhydrazine → HCID 18929398, compound

Participants

Reaction Steps

Methylhydrazine (1.9 g) was added dropwise to a solution of 5.0 g of 3,3-bis[methylthio]-1-(2,6-dichloro-4-trifluoromethylphenyl)-2-propen-1-one (22) in 50 ml of ethanol at room temperature, followed by refluxing for 3 hours. The solvent was distilled off under reduced pressure to obtain a residue, which was purified by column chromatography on silica gel, giving 1.6 g of the desired compound in the form of a brown oil (yield 28.5%).

Provenance & Evidence