反应详情

To 200 ml of acetic acid were added 26.4 g of 2-amino-indane and 44.5 g of phthalic anhydride, and the mixture was refluxed under heating for 17 hours. The reaction mixture was poured into ice water, and crystals precipitated were collected by filtration, washed, dried and then recrystallized from ethyl acetate to obtain 45.04 g of 2-(1,3-isoindolinedion-2-yl)indane.

1. temperaturethe mixture was refluxed
2. temperatureunder heating for 17 hours
3. customprecipitated
4. filtrationwere collected by filtration
5. washwashed
6. customdried
7. customrecrystallized from ethyl acetate