Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | HCID 67578113 | HCID 67578113 | — |
| Product | HCID 86752391 | HCID 86752391 | — |
Reaction Steps
An acetic acid (10 ml) solution of 7-[(1R,2R,3R)-3-hydroxy-2-(4,4-difluoro-7-methyl-3-oxooctyl)-5-oxocyclopentyl]heptanoic acid (6-1) (0.533 g) prepared as described in Example 2 was heated overnight at 70° C. The crude product obtained after the usual work up was chromatographed on silica gel eluted with a mixed solvent of dichloromethane and methanol (20/1) to yield the compound (6-2).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05739161 |
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| Source dataset | uspto-grants-1998_04 |
|---|
| ORD ID | ord-09f9432043f042d48e3ed38fcfad7f8c |
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| Source note | uspto-grants-1998_04 |
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