HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(4-methoxybenzoyl)-L-valyl-L-proline → (S)-1-[(S)-2-(4-methoxybenzamido)-3-methylbutyryl]-N-[2-methyl-1-(2,2,2-trifluoro 1-hydroxyethyl)propyl]pyrrolidine-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(4-methoxybenzoyl)-L-valyl-L-proline | HCID 10736489 | — |
| Reactant | 3-Amino-1,1,1-trifluoro-4-methylpentan-2-ol | HCID 14503246 | — |
| Product | (S)-1-[(S)-2-(4-methoxybenzamido)-3-methylbutyryl]-N-[2-methyl-1-(2,2,2-trifluoro 1-hydroxyethyl)propyl]pyrrolidine-2-carboxamide | HCID 10577353 | — |
Reaction Steps
reaction of N-(4-methoxybenzoyl)-L-valyl-L-proline with 3-amino-4-methyl-1,1,1-trifluoro-2-pentanol to give (S)-1-[(S)-2-(4-methoxybenzamido)-3-methylbutyryl]-N-[2-methyl-1-(2,2,2-trifluoro-1-hydroxyethyl)propyl]pyrrolidine-2-carboxamide; followed by
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05739157 |
| Source dataset | uspto-grants-1998_04 |
| ORD ID | ord-07f07f1d19f145b4b4e37044eceba6cf |
| Source note | uspto-grants-1998_04 |