HCID 18930577, compound → HCID 18930569, compound

HRID 1598915Notes

Reaction equation

HRID 1598915 reaction equation
C(OC(N(C1C=CC=CC=1)CC(NC1C=CC=CC=1C(C1C=CC=CC=1)=O)=O)=O)C=C.[CH2:32]([O:39][C:40]([N:42]1[CH2:47][CH2:46][CH:45]([C:48]([C:50]2[CH:56]=[CH:55][CH:54]=[CH:53][C:51]=2[NH2:52])=[O:49])[CH2:44][CH2:43]1)=[O:41])[C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=1.[CH2:57]([O:60][C:61]([C:63]1[CH:64]=[C:65]([NH:69][C:70](=[O:76])[NH:71][CH2:72][C:73](O)=[O:74])[CH:66]=[CH:67][CH:68]=1)=[O:62])[CH:58]=[CH2:59]>>[CH2:32]([O:39][C:40]([N:42]1[CH2:47][CH2:46][CH:45]([C:48]([C:50]2[CH:56]=[CH:55][CH:54]=[CH:53][C:51]=2[NH:52][C:73]([CH2:72][NH:71][C:70](=[O:76])[NH:69][C:65]2[CH:64]=[C:63]([CH:68]=[CH:67][CH:66]=2)[C:61]([O:60][CH2:57][CH:58]=[CH2:59])=[O:62])=[O:74])=[O:49])[CH2:44][CH2:43]1)=[O:41])[C:33]1[CH:34]=[CH:35][CH:36]=[CH:37][CH:38]=1

Participants

4

Reactant 3

HCID 18930577HCID 18930577, compoundHCID 18930641HCID 18930641, compound2×HCID 70146468HCID 70146468, compound

Product 1

HCID 18930569HCID 18930569, compoundYield 65.2%

Procedure

According to the method for the synthesis of the compound 6b, the titled compound (780 mg) is prepared using 2-(N-(benzyloxycarbonyl)piperidine-4-carbonyl)aniline (677 mg) and 2-(benzyloxycarbonylglycilamino)benzophenone (compound 46) (556 mg) as starting materials. Yield 65%.

Sources & evidence

ORD record
ord-1fc2315d7a6448a7829abc4ba0a67549
Source dataset
uspto-grants-1998_04
Patent number
US05739162

Reaction notes

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