HCID 18930600, compound → HCID 18930580, compound

Participants

Reaction Steps

tert-Butyl((2-(N-(benzyloxycarbonyl)piperidine-4-carbonyl)phenyl)-(2-(3-tolylureido)acetyl)amino)acetate and the compound 26 g (9.7 mg, 0.015 mmol) are dissolved in ethano. To the solution is added palladium hydrooxidecarbon powder (2 mg) and stirred under a hydrogen atmosphere (1 atm) at room temperature for 24 hours. The reaction solution is filtered and the filtrate is concentrated under reduced pressure. The residue is purified by silica gel column chromatography to obtain the objective compound 60 (6.0 mg). Yield 79%.

Provenance & Evidence