Trifluoroacetic acid → 5-{4-[2-(Indol-3-yl)ethoxy]benzyl}thiazolidine-2,4-dione

Participants

Reaction Steps

A procedure similar to that described in Example 2 was repeated, except that 1.77 g of 5-{4-[2-(indol-3-yl)ethoxy]benzyl}-3-triphenylmethylthiazolidine-2,4-dione (prepared as described in Preparation 11), 53 ml of methylene chloride and 0.3 ml of trifluoroacetic acid were used, to give 0.67 g of the title compound, melting at 42.6°-44.5° C.

Provenance & Evidence