6-Methoxy-N-methyl-3-nitropyridin-2-amine → 6-methoxy-2-N-methylpyridine-2,3-diamine

Participants

Reaction Steps

A procedure similar to that described in Example 6 was repeated, except that 3.45 g of 6-methoxy-2-methylamino-3-nitropyridine (prepared as described in Preparation 67), 0.70 g of 10% w/w palladium-on-charcoal and 50 ml of dioxane were used, to give 2.66 g of the title compound having Rf=0.12 (on silica gel thin layer chromatography using a 1:1 by volume mixture of hexane and ethyl acetate as the developing solvent).

Provenance & Evidence