反应详情

温度

130 °C

A suspension of 1-bromomethyl-4-chloro-2-ethoxycarbonyl-7-trifluoromethylimidazo[1,2-a]quinoxaline (91.0 g, 208 mmol) in glacial acetic acid (750 ml) was heated at 130° C. for 2.5 h. The solvent was removed under reduced pressure and the residue was stirred with ice-cooled water to give 81.2 g (93%) of the title compound. M.p. 247°-248° C.

1. customThe solvent was removed under reduced pressure
2. temperaturecooled water