反应详情

温度

60 °C

A suspension of 2-ethoxycarbonyl-1-(3,4-methylenedioxyanilino)methyl-7-trifluoromethylimidazo[1,2-a]quinoxalin-4(5H)-one (Example 13) (500 mg, 1.1 mmol) in 2M potassium hydroxide (50 ml) and methanol (50 ml) was stirred at 60° C. for 4 h. The reaction mixture was concentrated to half volume and the precipitate isolated by filtration to give 375 mg (74%) of the title compound as the potassium slat. M.p. >250° C.

1. concentrationThe reaction mixture was concentrated to half volume
2. customthe precipitate isolated by filtration