Isovaleryl chloride → HCID 9840009, compound

HRID 1599499Notes

Reaction equation

HRID 1599499 reaction equation
[OH:1][CH2:2][CH2:3][C:4]#[C:5][C:6]1[S:10][C:9]([C:11]2[S:12][CH:13]=[CH:14][CH:15]=2)=[CH:8][CH:7]=1.[C:16](Cl)(=[O:21])[CH2:17][CH:18]([CH3:20])[CH3:19]>N1C=CC=CC=1>[C:16]([O:1][CH2:2][CH2:3][C:4]#[C:5][C:6]1[S:10][C:9]([C:11]2[S:12][CH:13]=[CH:14][CH:15]=2)=[CH:8][CH:7]=1)(=[O:21])[CH2:17][CH:18]([CH3:20])[CH3:19]

Participants

4

Reactant 2

HCID 66054Isovaleryl chlorideHCID 4403573-Butyn-1-ol, 4-(5-(2-thienyl)-2-thienyl)-

Product 1

HCID 9840009HCID 9840009, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

5-(4-Hydroxy-1-butynyl)-2,2'-bithiophene (1 g) was dissolved in pyridine (10 ml). Isovaleroyl chloride (1 ml) was added at room temperature, stirred for few minutes and kept overnight. The reaction mixture was treated as in example 21. Light yellowish oily product (1.06 g) was then obtained.

Workup

  1. additionThe reaction mixture was treated as in example 21

Sources & evidence

ORD record
ord-786bb3b09fa54b19bcc4515ca9e498be
Source dataset
uspto-grants-1998_04
Patent number
US05741811

Reaction notes

Loading…