Sodium borohydride → HCID 54234997, compound

HRID 1599511Notes

Reaction equation

HRID 1599511 reaction equation
[CH:1]([C:3]1[S:7][C:6]([C:8]2[S:9][C:10]([C:13]3[CH:17]=[CH:16][S:15][CH:14]=3)=[CH:11][CH:12]=2)=[CH:5][CH:4]=1)=[O:2].[BH4-].[Na+]>CO>[OH:2][CH2:1][C:3]1[S:7][C:6]([C:8]2[S:9][C:10]([C:13]3[CH:17]=[CH:16][S:15][CH:14]=3)=[CH:11][CH:12]=2)=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 4311764Sodium borohydrideHCID 54240790HCID 54240790, compound

Product 1

HCID 54234997HCID 54234997, compoundYield 99.3%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of 5-formyl-2,2':5', 3"-terthiophene (0.5 g) in methanol (15 ml) was added excess amount of sodium borohydride. The reaction mixture was stirred at room temperature for 40 minutes. Methanol was removed and water was added. The solution was extracted with ethyl acetate, washed with brine, dried over anhydrous magnesium sulfate and concentrated to give brownish solid product (0.5 g), melting point 158°-160° C.

Workup

  1. customMethanol was removed
  2. additionwater was added
  3. extractionThe solution was extracted with ethyl acetate
  4. washwashed with brine
  5. dry with materialdried over anhydrous magnesium sulfate
  6. concentrationconcentrated

Sources & evidence

ORD record
ord-483bc1e4ad1a42b3bac7614c04a39718
Source dataset
uspto-grants-1998_04
Patent number
US05741811

Reaction notes

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