2-Methylcyclohexanone → HCID 54029495, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 1.5 g of 85% strength aqueous potassium hydroxide solution in 135 ml of water was charged to a 0.31 stainless-steel autoclave, and then 47.5 g of 2,4-dichlorobenzaldehyde and 30.5 g of 2-methylcyclohexanone were added, and the mixture was subsequently heated to 150° C. under the intrinsic pressure (to 3.8 bar). Stirring was subsequently carried out at this temperature for 10 hours. After cooling to room temperature, the suspension was filtered with suction and the solid product was washed to neutrality with water and dried in a vacuum oven at 55° C. In this way 62.8 g of 2-methyl-6-(2,4-dichlorobenzylidene)-cyclohexanone (99.5% pure) were obtained. This corresponds to a yield of 86% of theory.

Provenance & Evidence